Roitt's Essential Immunology: The Immune System Explained
# Roitt's Essential Immunology, 12th Edition - Introduction - What is immunology and why is it important? - What are the main topics covered in Roitt's Essential Immunology, 12th Edition? - Who are the authors and what are their credentials? - The Basis of Immunology - The cells and molecules of the immune system - Innate immunity: the first line of defense - Adaptive immunity: the specific response to pathogens - Antigen recognition by B cells and T cells - The generation of diversity in lymphocyte receptors - The Applied Immunology - Immune responses to infection: viral, bacterial, fungal and parasitic - Vaccination: principles and practice - Hypersensitivity: allergy and autoimmunity - Transplantation: rejection and tolerance - Tumor immunology: surveillance and escape - Immunodeficiency: primary and secondary - The Clinical Immunology - Diagnostic immunology: techniques and tests - Therapeutic immunology: drugs and antibodies - Immunotherapy: cytokines and vaccines - Conclusion - Summary of the main points and concepts of Roitt's Essential Immunology, 12th Edition - Benefits of using this textbook for students and instructors of immunology worldwide - FAQs - Where can I buy Roitt's Essential Immunology, 12th Edition? - How can I access the online resources that support this textbook? - What are the differences between the 12th edition and the previous editions? - How can I test my knowledge and understanding of immunology using this textbook? - What are some other recommended books on immunology? Here is the article based on the outline: # Roitt's Essential Immunology, 12th Edition ## Introduction Immunology is the study of how our body defends itself against foreign invaders, such as viruses, bacteria, fungi and parasites. It is a fascinating and complex field that has many applications in medicine, biotechnology, public health and research. Immunology is also a rapidly evolving discipline that incorporates new discoveries and technologies every year. If you are looking for a comprehensive, up-to-date and easy-to-read textbook on immunology, you should consider Roitt's Essential Immunology, 12th Edition. This book is the textbook of choice for students and instructors of immunology worldwide. It covers all the key principles and concepts of immunology, from the basis of immunity to clinical applications. It also provides a wealth of online resources to enhance your learning experience. The authors of Roitt's Essential Immunology, 12th Edition are Peter J. Delves, Seamus J. Martin, Dennis R. Burton and Ivan M. Roitt. They are all distinguished experts in their fields and have extensive teaching experience. They have written this book with the aim of making immunology accessible, engaging and relevant for students of all levels. ## The Basis of Immunology The first part of Roitt's Essential Immunology, 12th Edition introduces you to the basic components and mechanisms of the immune system. You will learn about: - The cells and molecules of the immune system: how they are organized, communicate and cooperate to protect us from infection. - Innate immunity: the first line of defense that consists of physical barriers, chemical mediators and cellular responses that act quickly and nonspecifically against pathogens. - Adaptive immunity: the specific response to pathogens that involves the activation, proliferation and differentiation of lymphocytes (B cells and T cells) that recognize antigens (foreign molecules) on pathogens. - Antigen recognition by B cells and T cells: how these lymphocytes use their unique receptors (antibodies for B cells and T cell receptors for T cells) to bind to antigens with high specificity and affinity. - The generation of diversity in lymphocyte receptors: how B cells and T cells produce a vast repertoire of receptors that can recognize virtually any antigen through a process of gene rearrangement, somatic mutation and selection. ## The Applied Immunology The second part of Roitt's Essential Immunology, 12th Edition explores how the immune system responds to different types of infection and how it can be manipulated for therapeutic purposes. You will learn about: - Immune responses to infection: how the immune system detects, eliminates and remembers viral, bacterial, fungal and parasitic infections using different strategies and effector mechanisms. - Vaccination: the principles and practice of inducing protective immunity against infectious diseases by administering antigens or attenuated pathogens. - Hypersensitivity: the abnormal and harmful immune reactions that cause allergy and autoimmunity, and the mechanisms and factors that underlie them. - Transplantation: the challenges and solutions of transferring organs, tissues or cells from one individual to another, and the role of immune tolerance and rejection. - Tumor immunology: the interactions between the immune system and cancer cells, and how the immune system can recognize, eliminate or promote tumor growth. - Immunodeficiency: the causes and consequences of impaired immune function, either due to genetic defects (primary immunodeficiency) or environmental factors (secondary immunodeficiency). ## The Clinical Immunology The third part of Roitt's Essential Immunology, 12th Edition focuses on the diagnostic and therapeutic applications of immunology in clinical settings. You will learn about: - Diagnostic immunology: the techniques and tests that are used to measure and evaluate the components and functions of the immune system in health and disease. - Therapeutic immunology: the drugs and antibodies that are used to modulate or enhance the immune system for the treatment of various disorders. - Immunotherapy: the use of cytokines (signaling molecules of the immune system) and vaccines to stimulate or suppress the immune system for the prevention or cure of diseases. ## Conclusion Roitt's Essential Immunology, 12th Edition is a comprehensive, up-to-date and easy-to-read textbook that covers all the key principles and concepts of immunology. It is suitable for students and instructors of immunology worldwide, regardless of their background or level of expertise. It also provides a wealth of online resources to support your learning, such as interactive questions, animations, videos, podcasts, figures, links and extracts. By using this textbook, you will gain a solid foundation and understanding of immunology that will enable you to apply your knowledge to various fields and situations. You will also develop your critical thinking and problem-solving skills that are essential for any scientific endeavor. ## FAQs - Where can I buy Roitt's Essential Immunology, 12th Edition? - You can buy Roitt's Essential Immunology, 12th Edition from various online platforms, such as Wiley, Amazon or Google Books. You can also find it in your local bookstore or library. - How can I access the online resources that support this textbook? - You can access the online resources that support this textbook by visiting www.roitt.com. You will need to register with your email address and create a password. You will also need to enter the code that is printed on the inside front cover of your book. - What are the differences between the 12th edition and the previous editions? - The 12th edition of Roitt's Essential Immunology has been revised and updated to reflect the latest advances and discoveries in immunology. It also has new illustrations, pedagogy and online resources to enhance your learning experience. Some of the new features include: - Just to recap... sections at the beginning of each chapter that remind you of key findings and principles - Summary sections at the end of each chapter that are ideal for quick study and revision - New chapters on diagnostic immunology, therapeutic immunology and immunotherapy - New animations and videos showing key concepts - New podcasts to reinforce the key principles explained in the text - How can I test my knowledge and understanding of immunology using this textbook? - You can test your knowledge and understanding of immunology using this textbook by answering the interactive questions that are available online for each chapter. These questions include multiple choice questions (MCQs) and single best answer questions (SBAs) that provide feedback on all answers selected. You can also use the self-assessment questions that are provided at the end of each chapter in the book. - What are some other recommended books on immunology? - Some other recommended books on immunology are: - Janeway's Immunobiology by Kenneth Murphy et al. - Cellular and Molecular Immunology by Abul Abbas et al. - How the Immune System Works by Lauren Sompayrac - The Immune System by Peter Parham
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