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// ameloblastic fibro-odontoma in a neonate: a case report. ameloblastic fibro-odontoma (afo) is a rare odontogenic tumor, initially described in the literature more than 50 years ago, and until recently it has been considered to be a variant of ameloblastic fibrodentinoma, with more recurrences. it affects both sexes equally and is usually diagnosed in early childhood. the tumor shows a predilection for the anterior mandible, as well as being associated with unerupted teeth. its clinical presentation consists of a swelling, with a slow or rapid growth rate and with or without pain. radiographically, it manifests as a mixed radiolucent/radiopaque lesion, well-defined, non-resorbed and often surrounded by an expanding radiolucent periapical lesion. diagnosis is achieved by a clinical and radiographic follow-up. we report an exceptional case of afo in a newborn with a fast growth rate and the first manifestation of the lesion at the neonatal period.a high-end-value retail professional and beauty brand, www.mermaidskin.